Dr. J.C. Murrell, sectie Anesthesiologie, Universiteitskliniek
voor Gezelschapsdieren, Faculteit Diergeneeskunde, UU
Effective pain management can only be achieved and maintained
when signs of pain can be assessed reliably and accurately.
The experience of pain is unique to each individual, and in
man this experience can be described verbally to facilitate
pain management. However in animals pain assessment is difficult,
often resulting in:
• Analgesics being withheld
because the animal is not showing overt signs of pain
• An assumption that since a human who has undergone
a similar procedure would require analgesics an animal must
also require pain relief, and therefore analgesics are administered
The result of the first scenario is animals that are almost
certainly in pain will not receive analgesia. In the second
case, since no proper assessment of the degree of pain is
made, it is a matter of chance whether an appropriate degree
of pain relief is given. In addition, although an initial
dose of analgesic is usually beneficial, and unlikely to be
detrimental to the animal, in the longer term repeated inappropriate
analgesic administration may also cause side effects. Therefore
it is clearly preferable to try and assess the animal's pain
and adjust the analgesic regimen on the basis of the assessment.
Numerous different methods of assessing pain have been developed
in man and attempts have been made to apply some of these
to animals. In verbal humans, scoring systems or pain questionnaires
(e.g. McGill pain questionnaire) are used to evaluate pain
and manage analgesic administration directly. However in infants
and babies, non verbal or written communication is not possible,
leading to similar difficulties with pain assessment to those
found in animals.
It is known that objective measures, including heart rate,
respiratory rate and body temperature are an unreliable guide
to the presence of pain (Holton
et al.1998). Therefore current methods to assess
clinical pain in animals are based primarily on behavioural
observations. However many factors can also influence behaviour
adding to difficulties in interpreting how much pain an animal
is experiencing. Animals undergoing diagnosis and treatment
of clinical disease are usually in an altered environment,
leading to changes in their normal behaviour that may mask
signs of pain. It is important to interpret pain in each species
based on the normal behaviour of that species. This is particularly
noticeable when pain behaviour in dogs and cats is compared.
Cats rarely vocalise in response to pain, but can become depressed
and sit hunched at the back of the cage, leading to the false
assumption that the animal is not in pain. The attention seeking
behaviour of many dogs in pain leads more readily to the administration
of analgesic drugs.
Recognition of pain in horses is also difficult and presents
a challenge to anaesthetists and equine practitioners in determining
analgesic drug administration. Few studies have investigated
postoperative pain in horses. Johnson et al. (1993) compared
the effects of three NSAIDs after elective orthopaedic surgery,
using a score, awarded after subjective evaluation of behaviour
by one of two assessors. McCarthy et al. (1993) measured plasma
b-endorphin concentration to assess pain and stress, but considered
it too non-specific to be useful. Raekallio et al. (1997a)
also attempted to quantify perioperative pain in horses after
elective orthopaedic procedures. Pain was scored subjectively,
and by measurement of predefined behavioural and physiological
values. Later Raekallio et al. (1997b),
using the same scoring system, investigated the analgesic
efficacy of phenylbutazone in horses after arthroscopy. A
poor correlation between the variables examined and perioperative
pain was found (Raekallio et al. 1997a,
1997b),
highlighting the difficulties of pain assessment in this species.
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